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 Contact Information:Deborah S. Nichols Larsen, PT, PhD
106 Atwell Hall
The Ohio State University
453 West Tenth Avenue
Columbus, OH 43210
Telephone: 614-292-5645
FAX: 614-292-0210
email: Deborah.Larsen@osumc.edu
Education:
Physical Therapy (B.S.), The Ohio State University, 1978
Education Psychology/Child Development (M.Ed.), University of Toledo, 1982
Psychobiology (Ph.D.), The Ohio State University, 1987
Clinical Expertise:
Pediatrics / neurology – private practice for 14 years
Professional Activities:
Member, American Physical Therapy Association
Pediatric Section
Education Section and the Academic Administrator's SIG
Neurology Section and Awards Committee
Chair, Ohio Council on Stroke Prevention and Education, 2003
Awards/Recognition:
2000, Research Award, School of Allied Medical Professions, OSU 1997, Sphinx Senior Honor Society, Honorary Member 1996, Phi Kappa Phi Honor Society 1995, Margaret L Moore Award for Outstanding Academic Faculty Member, APTA
Scholarly Activity:
My scholarship focuses on the recovery of function following neurologic injury, methods of measuring functional recovery, and the changes in the nervous system associated with that recovery. Currently, I participated in a national clinical trial (EXCITE) to evaluate the effectiveness of constraint –induced therapy for the recovery of arm function following stroke and a second multi-centered trial looking at the mapping of changes in the motor cortex associated with functional recovery of arm function after stroke, using functional magnetic resonance imaging and transcranial magnetic stimulation. We have also developed a new test of sensory function, which is undergoing testing and for which we have applied for a patent.
Publications (Past 10 Years):
Wolf SL, Winstein CJ, Miller JP, Thompson PA, Taub E, Uswatte G, Morris D, Blanton S, Nichols-Larsen D, Clark PC. Retention of upper limb function in stroke survivors who have received constraint-induced movement therapy: the EXCITE randomised trial. Lancet Neurol. 2008 Jan;7(1):33-40. Wolf SL, Winstein CJ, Miller JP, Blanton S, Clark PC, Nichols-Larsen D. Looking in the rear view mirror when conversing with back seat drivers: the EXCITE trial revisited. Neurorehabil Neural Repair. 2007 Sep-Oct;21(5):379-87. Wolf SL, Winstein CJ, Miller JP, Taub E, Uswatte G, Morris D, Giuliani C, Light KE, Nichols-Larsen D; EXCITE Investigators. Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trial. JAMA. 2006 Nov 1;296(17):2095-104.
Williams PG, Basso DM, Case-Smith J, Nichols-Larsen DS (2006) Development of a Hand active sensation test: reliability and Validity. Archives of Physical Medicine and Rehabilitation, 87:1471-7.
Nichols-Larsen DS, Clark PC, Zeringue A, Greenspan A, Blanton S. Factors influencing stroke survivors' quality of life during subacute recovery. Stroke. 2005 Jul;36(7):1480-4.
Casady RL, Nichols-Larsen DS. The effect of hippotherapy on ten children with cerebral palsy. Pediatr Phys Ther. 2004 Fall;16(3):165-72.
Winstein CJ, Miller JP, Blanton S, Taub E, Uswatte G, Morris D, Nichols D. Wolf S. Methods for a multisite randomized trial to investigate the effect of constraint-induced movement therapy in improving upper extremity function among adults recovering from a cerebrovascular stroke. Neurorehabil Neural Repair 2003;17:137-152 Levy C, Nichols D, Schmalbrook P. Functional MRI evidence of cortical reorganization in upper-limb stroke hemiplegia treated with constraint-induced movement therapy. American Journal of Phys Med & Rehabil 2001, 80 (1):4-12. Hart MC, Nichols DS, Butler EM, Barin K. Childhood imbalance and chronic otitis media with effusion: effect of typanostomy tube insertion on standardized tests of balance and locomotion. The Laryngoscope, 1998,108:665-670. Fishman M, Colby L, Sachs L, Nichols DS. Comparison of functional upper extremity balance tasks and force platform balance testing in hemiparesis. Physical Therapy. 1997;77:1052-1062. Nichols, D. Balance Retraining After Stroke Using Force Platform Biofeedback. Physical Therapy.1997;77:553-558. Wegener L, Kisner C, Nichols D. Static and dynamic balance responses in persons with bilateral knee osteoarthritis. Journal Orthopaedic & Sports Physical Therapy. 1997;25(1):13-18. Nichols D, Miller L, Colby L, Pease W. Sitting balance: its relation to function in individuals with hemiparesis. Archives of Phys Med Rehabil. 1996;77:865-869. Nichols D. Postural sway in young and old adults. Issues on Aging. 1996;19(1): 3-9. Nichols D, Case-Smith J. Reliability and validity analysis of the Pediatric Evaluation of Disability Inventory. Pediatric Physical Therapy. 1996;8(1);15-24. Nichols D, Glenn T, Hutchinson K. Changes in the mean center of balance during testing in young adults. Physical Therapy. 1995; 75(8):699-706. Mruzek M, Barin K, Nichols D, Burnett C, Welling D. Effects of vestibular rehabilitation and social reinforcement on recovery following ablative vestibular surgery. The Laryngoscope. 1995; 105(6):686-692. Nichols D, Glenn T. Effects of aerobic exercise on pain perception, affect, and level of disability in individuals with fibromyalgia. Physical Therapy;1994,74(4):327-332. Fun Facts:I am the proud mother of two almost adult sons, John and Mark, and was recently married to Glenn (a geologist). I am also the owner of two large dogs, Cosmo (a lab/retriever/Chow mix) and Lucy (mostly a Harlequin Great Dane). I’m a Buckeye fan through and through, having earned 2 of my degrees here, and even have a scarlet and gray office. I love all sports, especially Buckeye sports, and play soccer two to three nights/week (yes play), which is how I met my husband, who is a goalie.
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